Ionis Pharmaceuticals Inc
Active WDID 9 37I014738 Carlsbad, San Diego County Region 9 · San Diego
At a glance
- Permit Evidence: SMARTS record
- Active Industrial
- Notice of Intent (WDID code I) · Permits and applications
- Location Evidence: facility-reported
- Carlsbad, San Diego County
- Region 9 · San Diego · Location · Statewide map
- Receiving water
- Agua Hedionda Creek (as reported by the facility)
- Evidence: identification corroborated Agua Hedionda Creek Details
- Identified receiving water on the 2026 303(d) list
- Yes · 17 Appendix A decisions, category 5 Evidence: State-published
- Describes the waterbody, not this facility · Waterbody profile
- 2026 Integrated Report waters within 1.0 km Evidence: geographic proximity
- 1 waterbody; 1 on the 2026 303(d) list
- Proximity only; not a discharge pathway · Nearby waterbodies
- Monitoring results Evidence: facility-reported
- 69 distinct results, 10 reporting years (2015 to 2025)
- Most recent sample Feb 11, 2026 · Monitoring
- Compliance and enforcement records Evidence: SMARTS record
- 1 inspection · 1 violation record · 0 enforcement actions
- Counts as published in SMARTS; not a compliance determination · Details
Each label shows where a statement comes from. How to read the labels.
Overview and location
Reported facility location HUC12 watershed Corroborated receiving water 2026 Integrated Report waterbodies nearby
Reported location Evidence: facility-reported
- Coordinates
- 33.13473, -117.27681
- Precision
- 5 decimal places
- Shared point
- No
- Matches application record
- same
Facility location as reported by the discharger in SMARTS; not a discharge point or outfall.
- Facility address
- 2282 Faraday Ave, Carlsbad 92008
- Regional Water Board
- 9 — San Diego
HUC12 watershed Evidence: spatial
- Agua Hedionda Creek HUC12 180703030502
The facility's reported location lies within this HUC12 watershed (spatial derivation); it is not a discharge location.
Permits and applications Evidence: SMARTS record
Current permit record
- Permit type
- Industrial
- Application type
- Notice of Intent (WDID code I)
- Status
- Active
- Operator
- lonis Pharmaceuticals Inc
- Primary industry (SIC)
- 2834-Pharmaceutical Preparations
- Application ID
- 218658
- NOI processed
- Nov 12, 1998
- Last certified
- May 26, 2015
- Facility size
- 4 Acres
- Impervious area
- 95 %
Retrieved from SMARTS Oct 20, 2026. Verify against SMARTS before relying on it.
Permit history
| Application | Type | Status | Processed | Terminated | Certified |
|---|---|---|---|---|---|
| 218658 | Industrial | Active | Nov 12, 1998 | — | May 26, 2015 |
Every storm water application SMARTS records for this WDID, newest first (1).
Receiving water
- Reported by the facility Evidence: facility-reported
- Agua Hedionda Creek
- Discharges directly / indirectly
- N / Y (as answered in the permit application)
Evidence: identification corroborated Agua Hedionda Creek CAR9043100020010924145051
Receiving water reported by facility — waterbody identification corroborated by geographic evidence.
Nearest distance from the reported facility location: 909 m. Method receiving_water/2.
2026 Integrated Report status Evidence: State-published
Agua Hedionda Creek is on the 2026 Clean Water Act section 303(d) list (17 Appendix A decisions; category 5).
| Pollutant | Category | Listing decision | TMDL requirement | Decision ID |
|---|---|---|---|---|
| Benthic Community Effects | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 125884 |
| Bifenthrin | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 111604 |
| Chlorpyrifos | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 111585 |
| Cyfluthrin | 5 | List on 303(d) list (TMDL required list) | 5A | 111610 |
| Cyhalothrin, Lambda | 5 | List on 303(d) list (TMDL required list) | 5A | 111612 |
| Cypermethrin | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 144941 |
| Deltamethrin | 5 | List on 303(d) list (TMDL required list) | 5A | 144942 |
| Indicator Bacteria | 5 | List on 303(d) list (TMDL required list) | 5A | 75644 |
| Malathion | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 111591 |
| Manganese | 5 | List on 303(d) list (TMDL required list) | 5A | 68777 |
| Nitrogen | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 132037 |
| Phosphorus | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 111596 |
| Pyrethroids | 5 | List on 303(d) list (TMDL required list) | 5A | 144940 |
| Selenium | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 111597 |
| Total Dissolved Solids | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 111598 |
| Toxicity | 5 | Do Not Delist from 303(d) list (TMDL required list) | 5A | 111599 |
| Turbidity | 5 | List on 303(d) list (TMDL required list) | 5A | 111600 |
Published by the State Water Resources Control Board (2026 California Integrated Report, Appendix A). Listing status is taken from Appendix A only. State Board adoption 2026-02-03; USEPA approval not confirmed. A listing describes the waterbody, not this facility. Waterbody profile.
Impaired waters and TMDLs
Two kinds of information, kept apart: 2026 Integrated Report waterbodies near the reported location (geographic proximity only), and TMDL records that SMARTS lists for this facility. Neither establishes where the facility discharges; see Receiving water for the facility's own statement.
Nearby waterbodies Evidence: geographic proximity
Spatial proximity only; discharge pathway not established. Being near a waterbody does not mean the facility discharges to it.
| Waterbody (2026 Integrated Report) | Distance | 2026 303(d) list | Appendix A decisions |
|---|---|---|---|
| Agua Hedionda Creek CAR9043100020010924145051 | 909 m | listed | 17 |
Waterbodies within 1.0 km of the reported facility location. Method proximity/1.
SMARTS TMDL records Evidence: SMARTS-reported
No TMDL records for this facility in the SMARTS TMDL export.
Reported monitoring results Evidence: facility-reported
Numeric Action Level (NAL) screening is being independently validated and is not shown. Nothing on this page states whether a result exceeded a NAL.
69 distinct measurements across 3 parameters, most recent sample Feb 11, 2026.
By reporting year
| Reporting year (July–June) | Distinct results | Parameters | With several versions | First sample | Last sample |
|---|---|---|---|---|---|
| 2025 | 6 | 3 | 0 | Nov 14, 2025 | Feb 11, 2026 |
| 2023 | 6 | 3 | 0 | Nov 16, 2023 | Jan 22, 2024 |
| 2022 | 6 | 3 | 0 | Sep 09, 2022 | Jan 05, 2023 |
| 2021 | 6 | 3 | 0 | Oct 05, 2021 | Feb 23, 2022 |
| 2020 | 3 | 3 | 0 | Jan 29, 2021 | Jan 29, 2021 |
| 2019 | 6 | 3 | 0 | Nov 20, 2019 | Jan 17, 2020 |
| 2018 | 6 | 3 | 0 | Oct 04, 2018 | Jan 14, 2019 |
| 2017 | 6 | 3 | 0 | Jan 09, 2018 | Feb 27, 2018 |
| 2016 | 12 | 3 | 0 | Sep 20, 2016 | Jan 20, 2017 |
| 2015 | 12 | 3 | 0 | Sep 09, 2015 | Mar 14, 2016 |
By parameter
| Parameter | Units | Measurements | Below detection | First sample | Last sample | Results |
|---|---|---|---|---|---|---|
| Oil and Grease | mg/L | 23 | 9 | Sep 09, 2015 | Feb 11, 2026 | Results |
| pH | SU | 23 | 0 | Sep 09, 2015 | Feb 11, 2026 | Results |
| Total Suspended Solids (TSS) | mg/L | 23 | 2 | Sep 09, 2015 | Feb 11, 2026 | Results |
All results (69 distinct rows)
| Sample date | Parameter | Result | Units | Location type | Event | Method | Report | Versions |
|---|---|---|---|---|---|---|---|---|
| Feb 11, 2026 | Oil and Grease | ND | mg/L | Effluent | Qualifying Storm Event | E1664A | 1373651 | |
| Feb 11, 2026 | pH | 6 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1373651 | |
| Feb 11, 2026 | Total Suspended Solids (TSS) | 2 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1373651 | |
| Nov 14, 2025 | Oil and Grease | ND | mg/L | Effluent | Qualifying Storm Event | E1664A | 1359869 | |
| Nov 14, 2025 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1359869 | |
| Nov 14, 2025 | Total Suspended Solids (TSS) | 4.5 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1359869 | |
| Jan 22, 2024 | Oil and Grease | ND | mg/L | Effluent | Qualifying Storm Event | E1664A | 1278343 | |
| Jan 22, 2024 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1278343 | |
| Jan 22, 2024 | Total Suspended Solids (TSS) | 1 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1278343 | |
| Nov 16, 2023 | Oil and Grease | ND | mg/L | Effluent | Qualifying Storm Event | E1664A | 1269325 | |
| Nov 16, 2023 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1269325 | |
| Nov 16, 2023 | Total Suspended Solids (TSS) | 1.6 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1269325 | |
| Jan 05, 2023 | Oil and Grease | ND | mg/L | Effluent | Qualifying Storm Event | E1664A | 1225872 | |
| Jan 05, 2023 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1225872 | |
| Jan 05, 2023 | Total Suspended Solids (TSS) | ND | mg/L | Effluent | Qualifying Storm Event | A2540D | 1225872 | |
| Sep 09, 2022 | Oil and Grease | 8 | mg/L | Effluent | Qualifying Storm Event | E1664A | 1214948 | |
| Sep 09, 2022 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1214948 | |
| Sep 09, 2022 | Total Suspended Solids (TSS) | 24 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1214948 | |
| Feb 23, 2022 | Oil and Grease | ND | mg/L | Effluent | Qualifying Storm Event | E1664A | 1178685 | |
| Feb 23, 2022 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1178685 | |
| Feb 23, 2022 | Total Suspended Solids (TSS) | 7.7 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1178685 | |
| Oct 05, 2021 | Oil and Grease | ND | mg/L | Effluent | Qualifying Storm Event | E1664A | 1167790 | |
| Oct 05, 2021 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1167790 | |
| Oct 05, 2021 | Total Suspended Solids (TSS) | 3 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1167790 | |
| Jan 29, 2021 | Oil and Grease | 2.7 | mg/L | Effluent | Qualifying Storm Event | E1664B | 1143416 | |
| Jan 29, 2021 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1143416 | |
| Jan 29, 2021 | Total Suspended Solids (TSS) | ND | mg/L | Effluent | Qualifying Storm Event | A2540D | 1143416 | |
| Jan 17, 2020 | Oil and Grease | 1.7 | mg/L | Effluent | Qualifying Storm Event | E1664A | 1099816 | |
| Jan 17, 2020 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1099816 | |
| Jan 17, 2020 | Total Suspended Solids (TSS) | 1.3 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1099816 | |
| Nov 20, 2019 | Oil and Grease | 1.4 | mg/L | Effluent | Qualifying Storm Event | E1664A | 1090951 | |
| Nov 20, 2019 | pH | 6 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1090951 | |
| Nov 20, 2019 | Total Suspended Solids (TSS) | 11 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1090951 | |
| Jan 14, 2019 | Oil and Grease | 1.8 | mg/L | Effluent | Qualifying Storm Event | E1664A | 1040518 | |
| Jan 14, 2019 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1040518 | |
| Jan 14, 2019 | Total Suspended Solids (TSS) | 1.6 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1040518 | |
| Oct 04, 2018 | Oil and Grease | 2.3 | mg/L | Effluent | Qualifying Storm Event | E1664A | 1026755 | |
| Oct 04, 2018 | pH | 6 | SU | Effluent | Qualifying Storm Event | pH_Paper | 1026755 | |
| Oct 04, 2018 | Total Suspended Solids (TSS) | 3 | mg/L | Effluent | Qualifying Storm Event | A2540D | 1026755 | |
| Feb 27, 2018 | Oil and Grease | < 1 | mg/L | Effluent | Qualifying Storm Event | E1664A | 994472 | |
| Feb 27, 2018 | pH | 6 | SU | Effluent | Qualifying Storm Event | pH_Paper | 994472 | |
| Feb 27, 2018 | Total Suspended Solids (TSS) | 4 | mg/L | Effluent | Qualifying Storm Event | A2540D | 994472 | |
| Jan 09, 2018 | Oil and Grease | 2 | mg/L | Effluent | Qualifying Storm Event | E1664A | 990088 | |
| Jan 09, 2018 | pH | 6.5 | SU | Effluent | Qualifying Storm Event | pH_Paper | 990088 | |
| Jan 09, 2018 | Total Suspended Solids (TSS) | 2 | mg/L | Effluent | Qualifying Storm Event | A2540D | 990088 | |
| Jan 20, 2017 | Oil and Grease | < 1 | mg/L | Effluent | Qualifying Storm Event | E1664A | 925706 | |
| Jan 20, 2017 | pH | 7 | SU | Effluent | Qualifying Storm Event | A4500HB | 925706 | |
| Jan 20, 2017 | Total Suspended Solids (TSS) | 1 | mg/L | Effluent | Qualifying Storm Event | A2540D | 925706 | |
| Jan 05, 2017 | Oil and Grease | 1.1 | mg/L | Effluent | Qualifying Storm Event | A5220B | 925688 | |
| Jan 05, 2017 | pH | 7 | SU | Effluent | Qualifying Storm Event | pH_Paper | 925688 |
Results are shown exactly as reported by the discharger. Identical rows repeated in the State's export are shown once. Where the export contains different versions of the same sample and parameter, each version is listed and flagged. Details.
Compliance and enforcement records Evidence: SMARTS record
These are records as the State Water Board publishes them in SMARTS, with the source's own types and statuses. They are not a compliance determination or rating. A record listed here is not proof of a violation beyond what the source states, and the absence of records does not establish compliance.
| Record type | Records | As published | Dates | Retrieved | List |
|---|---|---|---|---|---|
| Violations | 1 | 1 Violation · 0 Potential (preliminary) · 0 Dismissed | Jul 02, 1999 – Jul 02, 1999 | Oct 21, 2026 | All violations |
| Enforcement actions | 0 | 0 issued · 0 draft · 0 withdrawn, rescinded or superseded | — | Oct 21, 2026 | |
| Inspections | 1 | inspections, not findings | Sep 26, 2001 – Sep 26, 2001 | Oct 21, 2026 | All inspections |
| Annual reports | 11 | certified reports (contents not shown) | 2015 – 2025 | Oct 21, 2026 | All reports |
| Water-quality-based corrective action reports | 0 | reports, by parameter | — | Oct 21, 2026 |
Each record type is counted by its own SMARTS identifier. A violation and the enforcement action that cites it are two records in two lists; they are never added together.
Chronological record history (13 records, newest first)
| Date | Record | ID | Type or purpose | Status as published | Detail |
|---|---|---|---|---|---|
| Jun 09, 2026 | Annual reports | 1336738 | Annual report 2025 | — | |
| Jun 13, 2025 | Annual reports | 1295616 | Annual report 2024 | — | |
| Jun 14, 2024 | Annual reports | 1244771 | Annual report 2023 | — | |
| Jun 06, 2023 | Annual reports | 1190845 | Annual report 2022 | — | |
| Jun 14, 2022 | Annual reports | 1114350 | Annual report 2021 | — | |
| Jun 02, 2021 | Annual reports | 1070434 | Annual report 2020 | — | |
| Jun 04, 2020 | Annual reports | 987824 | Annual report 2019 | — | |
| Jun 03, 2019 | Annual reports | 955450 | Annual report 2018 | — | |
| Jun 14, 2018 | Annual reports | 940871 | Annual report 2017 | — | |
| Jun 02, 2017 | Annual reports | 880224 | Annual report 2016 | — | |
| Jun 29, 2016 | Annual reports | 843062 | Annual report 2015 | — | |
| Sep 26, 2001 | Inspections | 312953 | B Type compliance | — | |
| Jul 02, 1999 | Violations | 178959 | Deficient Report | Violation | Inspection |
Sources and provenance
| Information | Source | Retrieved or published |
|---|---|---|
| Permit, location, receiving-water text | SMARTS Industrial Application Specific Data | Oct 20, 2026 |
| Permit history | SMARTS Storm Water Applications | Oct 20, 2026 |
| Monitoring results | SMARTS Industrial Parameter Data | Oct 20, 2026 |
| Watershed Boundary Dataset HU2 GeoPackages 15, 16, 18 (WBDHU12) | USGS | 2026-10-22 |
| 2026 California Integrated Report, Appendix A: 2026 303(d) List (final) | SWRCB | 2026-10-22 |
| Final_2026_Rivers_and_Streams + Final_2026_Lakes_and_Reservoirs (FeatureServer 0) | SWRCB GIS | 2026-10-22 |
| SMARTS TMDL requirements | SMARTS | 2026-10-21 |
Relationships computed 2026-10-22 with methods facility_huc12/1, proximity/1, receiving_water/2, tmdl_reference/1, waterbody_huc12_ovl/1, waterbody_huc12_pub/1; proximity threshold 1.0 km.
How to read the evidence labels
- Evidence: SMARTS record Evidence: facility-reported Information as published in SMARTS or reported by the discharger.
- Evidence: identification corroborated The reported receiving-water name identifies one official waterbody and the facility's location is consistent with it. It does not establish a discharge pathway.
- Evidence: candidate, awaiting review Evidence: not confirmed The reported name could match one or more official waterbodies, but no identification has been confirmed; nothing is assigned without review.
- Evidence: spatial Evidence: geographic proximity Derived from the reported location only.
- Evidence: SMARTS-reported Source records whose links to official references are not yet reviewed.
- Evidence: unavailable The information could not be loaded or is not in the sources.
Records are shown as published and are not compliance determinations. How geographic context is derived.